Clinical manifestations HSE
HSE is acute or subacute with focal and general signs of cerebral dysfunction. Are sporadic and not associated with the pattern of a particular season. Although fever, headache, behavioral changes, confusion, focal neurological abnormalities and abnormalities in CSF supports the HSE, there are no clinical signs patognomonis to distinguish HSE from other neurological diseases (eg non-HSV encephalitis, brain abscess or brain tumor). Confirmation of the diagnosis depends on identification of HSV from CSF examination by PCR or in brain tissue with brain biopsy.
Typical clinical symptoms that arise include: fever, headache, psychiatric symptoms, seizures, vomiting, focal muscle weakness, memory loss, impaired mental status, photo phobia, and movement disorders.
Physical examination of the most common are fever and mental status abnormalities, whereas meningismus rare. Peripheral lesions (eg herpes labialis) had no relationship with HSE; presence or absence of lesions are not helpful in confirmation of the diagnosis of HSE.
It typically encountered include: disturbance of consciousness, fever, disfasia, ataxia, focal seizures, including seizures and convulsions general, hemiparesis, brain defects, loss of visual field and papil edema.
Differential diagnosis of HSE is a brain abscess, encephalitis, epidural and subdural infections, brain neoplasms, febrile seizures, meningitis, CVA hemorrhage and brain ischemia.
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