Clinical manifestations HSE
HSE is acute or subacute with focal and general signs of cerebral dysfunction. Are sporadic and not associated with the pattern of a particular season. Although fever, headache, behavioral changes, confusion, focal neurological abnormalities and abnormalities in CSF supports the HSE, there are no clinical signs patognomonis to distinguish HSE from other neurological diseases (eg non-HSV encephalitis, brain abscess or brain tumor). Confirmation of the diagnosis depends on identification of HSV from CSF examination by PCR or in brain tissue with brain biopsy.