Herpes simplex is a viral infection characterized by localized primary lesion, latency and the tendency for recurrence. There are 2 types of virus - the herpes simplex virus (HSV) types 1 and 2 in general lead to different clinical symptoms, depending on the entry road. Can attack the means of genital or oral mucosa. Primary infection with HSV-1 may be mild with no symptoms, occurred in early childhood.
Approximately 10% of primary infection, emerged as a disease with a diverse spectrum of clinical symptoms, characterized by hot and malaise to 1 week or more, may be accompanied by severe gingivostomatitis followed by a vesicular lesions on the oropharynx, severe keratoconjunctivitis, and accompanied by the emergence of symptoms and complications of chronic eczema-like skin, meningoencephalitis or some fatal infection that occurs in newborns (congenital herpes simplex, ICD-9 771.2, ICD-10 P35.2).